She's self-righteous, shoving her views and her way down people's throats whether they ask for it or not, refusing to accept people's choices regarding their own lives if they don't match up with her views.

She's pretending (or actually trying, idk) to only want to help people, and uses it as justification for everything she does, whether it ends up helding people or hurting them.

And on the flipside, as soon as someone treats her that way, she blows it out of proportion and feels attacked.

I think I could sum it up as she has higher standards for other people than she does for herself?

That, and the whole drama about wanting to be with House. Or not. Which is not a personality thing, but still bothers me about the character.